What are the Limitations of HPV DNA Detection in Histological Samples?
While HPV DNA detection in histological samples is highly informative, it has some limitations. The sensitivity and specificity of the tests can vary, leading to false positives or negatives. Also, the presence of HPV DNA does not always correlate with disease severity, as some infections can be transient and asymptomatic. Furthermore, technical issues like sample quality and the choice of detection method can affect the results.
