Detection of HPV DNA in histology involves several techniques. The most common method is [In Situ Hybridization (ISH)](https://), which allows for the localization of HPV DNA within the tissue samples. Another technique is [Polymerase Chain Reaction (PCR)](https://), which amplifies the DNA sequences to detectable levels. Immunohistochemistry (IHC) can also be used to detect HPV-associated proteins, providing indirect evidence of the presence of HPV DNA.
