What are the Limitations of Histological Studies in Pathophysiology?
While histology provides valuable insights, it has limitations:
1. Sample Representation: Biopsies may not capture the full extent of a disease, leading to sampling bias. 2. Observer Variability: Interpretation of histological images can be subjective, with variations between pathologists. 3. Static Nature: Traditional histological techniques offer a snapshot in time, lacking dynamic information about disease progression.
