What are the Key Stages of Neural Plate Development?
1. Induction: The notochord induces the overlying ectoderm to form the neural plate. 2. Shaping: The neural plate elongates and narrows, a process regulated by cellular mechanisms such as convergent extension. 3. Folding: The lateral edges of the neural plate elevate to form neural folds. 4. Closure: The neural folds converge at the midline and fuse to form the neural tube, which will further differentiate into the brain and spinal cord.