Several proteins and factors are critical in ribosome biogenesis. These include:
Ribosomal Proteins: Essential for the structural integrity and function of the ribosome. Nucleolin: Involved in the processing and assembly of rRNA. Fibrillarin: A snoRNA-associated protein that guides rRNA modifications. Exportins: Proteins that facilitate the transport of ribosomal subunits from the nucleus to the cytoplasm. GTPases: Enzymes that provide energy for the assembly and transport processes.