What are the Key Molecules Released During Degranulation?
The molecules released during degranulation are diverse and include:
- Histamines: Involved in increasing vascular permeability and smooth muscle contraction. - Proteases: Such as tryptase and chymase, which can degrade extracellular matrix components. - Cytokines: Like TNF-α and IL-4, which modulate inflammation and immune responses. - Chemokines: Attract other immune cells to the site of inflammation or infection.
