What Are the Key Findings from TCGA Related to Histology?
TCGA has led to numerous significant discoveries, including: - Identification of novel molecular subtypes of cancers that correlate with distinct histological features. - Insights into the tumor microenvironment, including the roles of immune cells and stromal components in cancer progression. - Discovery of histologically distinct regions within the same tumor that have different genomic profiles, highlighting the importance of tumor heterogeneity.