What are the implications of CDC42 dysfunction in diseases?
Dysregulation of CDC42 is implicated in numerous diseases, including cancer, neurodegenerative disorders, and immune deficiencies. In cancer, abnormal CDC42 activity can lead to unchecked cell proliferation, invasion, and metastasis. In the nervous system, CDC42 mutations are associated with developmental disorders and impaired neuronal function. Understanding CDC42’s role in these diseases can inform therapeutic strategies and diagnostic tools.
