CVS can be conducted either transcervically or transabdominally. In the transcervical approach, a thin catheter is inserted through the cervix to access the placenta, while in the transabdominal approach, a needle is inserted through the abdomen. Both methods involve the collection of a small sample of chorionic villi, which is then sent to a laboratory for analysis. The choice between the two approaches depends on factors such as the position of the placenta and the preference of the healthcare provider.