What are the Histological Features of Pheomelanin?
In histological sections, pheomelanin can be identified using various staining techniques. Due to its chemical composition, pheomelanin is less reactive to silver stains compared to eumelanin. Advanced techniques such as immunohistochemistry and mass spectrometry can also be used to differentiate pheomelanin from other pigments. Ultrastructurally, pheomelanin granules are smaller and more irregular in shape compared to eumelanin granules.