What Are the Immune Considerations During Implantation?
The maternal immune system has to tolerate the semi-allogenic embryo.
- Immune Tolerance: The presence of regulatory T cells and the expression of immune-modulatory molecules like HLA-G on trophoblast cells help in preventing maternal immune rejection. - Cytokines and Chemokines: These signaling molecules are involved in modulating the local immune environment to favor implantation.