What Are the Histological Effects of Pesticides on Different Organs?
Liver The liver is one of the primary organs affected by pesticide exposure. Histological examination often shows signs of hepatotoxicity, including cellular necrosis, fatty changes, and fibrosis. These changes can disrupt liver function and contribute to diseases such as cirrhosis and liver cancer.
Kidney Pesticides can also affect the kidneys, leading to nephrotoxicity. Histological features may include glomerular damage, tubular necrosis, and interstitial fibrosis. These alterations can impair kidney function, leading to chronic kidney disease.
Brain Neurotoxicity is another significant concern related to pesticide exposure. Histological studies of brain tissue may reveal neuronal degeneration, glial cell proliferation, and the formation of abnormal protein aggregates. These changes are often associated with neurodegenerative diseases like Parkinson's and Alzheimer's.
