What are Some Disorders Associated with the Granular Layer?
Several skin disorders are associated with abnormalities in the granular layer. These include:
Ichthyosis Vulgaris: A condition characterized by dry, scaly skin due to mutations affecting filaggrin. Atopic Dermatitis: A chronic inflammatory skin condition often linked to defects in the skin barrier, including abnormalities in the granular layer. Psoriasis: A condition where the turnover rate of epidermal cells is accelerated, leading to an abnormal structure and function of the granular layer.
