What Are the Histological Changes in the Kidneys Due to NSAIDs?
NSAIDs can also impact renal histology, particularly in susceptible individuals. The inhibition of prostaglandins affects renal blood flow and can lead to:
Acute Interstitial Nephritis: Characterized by inflammation of the interstitial tissue, often with infiltration of immune cells. Chronic Kidney Disease: Long-term use can lead to chronic damage, including fibrosis and tubular atrophy.
