pathogenesis of infectious diseases

What Are the Histological Changes in Infected Tissues?

Infected tissues exhibit characteristic histological changes depending on the type of pathogen and the body's immune response. Common histological features include:
Inflammation: The accumulation of immune cells such as neutrophils, macrophages, and lymphocytes is a hallmark of infection.
Necrosis: Cell death due to direct pathogen damage or immune-mediated mechanisms.
Granuloma formation: A chronic inflammatory response often seen in infections like tuberculosis, resulting in a structured mass of immune cells.
Fibrosis: The deposition of collagen and other extracellular matrix components as a result of chronic inflammation.

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