What are the future research directions for NKX2.5?
Future research on NKX2.5 aims to further elucidate its role in heart development and disease. This includes understanding the detailed molecular mechanisms by which NKX2.5 regulates cardiac gene expression and how its dysregulation leads to congenital heart defects. Advances in CRISPR/Cas9 technology and other genome-editing tools offer new avenues to study NKX2.5 function in vivo. Furthermore, research is focused on identifying novel interacting partners and downstream targets of NKX2.5, which can provide deeper insights into its regulatory networks.
