Research is ongoing to better understand the UPS: - Identifying New E3 Ligases: Discovering novel E3 ligases and their substrates can provide insights into specific cellular pathways. - Developing Specific Inhibitors: Creating more specific inhibitors for the UPS components can lead to targeted therapies with fewer side effects. - Studying UPS in Different Tissues: Examining how the UPS functions in various tissues can uncover tissue-specific roles and disease mechanisms.
