Transcriptional Activation: UBF binds to rDNA and helps in recruiting RNA polymerase I, initiating the transcription of rRNA. Chromatin Remodeling: UBF helps in maintaining an open chromatin structure, which is necessary for active transcription. Cell Growth and Proliferation: By regulating rRNA synthesis, UBF indirectly influences cell growth and proliferation, making it a vital component in rapidly dividing cells.
