Diagnosis of tubulointerstitial changes typically involves a combination of clinical assessment, laboratory tests, and histological examination. Key diagnostic methods include:
- Renal Biopsy: A tissue sample examined under a microscope to identify specific histological features such as inflammatory cell infiltration, fibrosis, and tubular atrophy. - Immunohistochemistry: Techniques to detect specific markers of inflammation and fibrosis in renal tissue sections. - Imaging Studies: Ultrasound and CT scans can help assess structural changes in the kidneys.
