While the presence of fatty casts is a strong indicator of underlying renal pathology, their detection can be challenging due to several factors:
- Sample Collection: Improper collection of urine samples can lead to degradation of casts. - Microscopy Skills: Accurate identification requires expertise in microscopic techniques and familiarity with the appearance of different types of casts. - Overlapping Features: Fatty casts may sometimes be confused with other types of casts or debris, necessitating the use of specific staining techniques and polarized light microscopy for confirmation.