What are the Components Released During Degranulation?
During degranulation, mast cells release a variety of bioactive substances, including:
Histamine: Causes vasodilation and increased vascular permeability, leading to swelling and redness. Heparin: An anticoagulant that prevents blood clotting. Proteases: Enzymes that break down proteins and contribute to tissue remodeling. Cytokines: Signaling molecules that recruit and activate other immune cells. Chemokines: Chemotactic agents that attract immune cells to the site of inflammation.
