What are the Common Staining Techniques Used in Muscle Histology?
Several staining techniques are employed to highlight different aspects of muscle tissue:
- Hematoxylin and Eosin (H&E): Provides a general overview of muscle tissue architecture. - Gomori Trichrome: Useful for detecting fibrosis and mitochondrial abnormalities. - Periodic Acid-Schiff (PAS): Highlights glycogen storage within muscle fibers. - Immunohistochemistry: Uses antibodies to detect specific proteins, aiding in the diagnosis of conditions like muscular dystrophies and myositis.