- Incomplete Clearing: This can result from insufficient dehydration or inadequate clearing time. Ensure proper dehydration and extend the clearing time if necessary. - Tissue Hardening: Overexposure to clearing agents can harden tissues. Use the minimal effective time and concentration of the clearing agent. - Health and Safety Concerns: Many clearing agents are toxic and flammable. Use appropriate personal protective equipment (PPE), work in a well-ventilated area, and follow safety protocols.
