What Are the Common Histological Changes in Low FVC Ratio?
In conditions where the FVC ratio is low, such as chronic obstructive pulmonary disease (COPD) or asthma, histologists often observe bronchial wall thickening, mucus hypersecretion, and smooth muscle hypertrophy. These changes narrow the airways and restrict airflow, primarily affecting the FEV1 value more significantly than the FVC, resulting in a lower ratio.
