What Are the Common Artifacts in Tissue Preparation?
Artifacts are distortions or errors in tissue samples that can arise at any stage of preparation. Common artifacts include:
- Shrinkage: Often due to improper fixation or dehydration. - Folding: Occurs during sectioning or mounting, obscuring tissue details. - Air Bubbles: Introduced during mounting, can interfere with microscopic examination. - Staining Artifacts: Uneven or nonspecific staining can obscure or mimic pathological changes.
