What are the Clinical Implications of Transthyretin in Histology?
The accumulation of TTR as amyloid deposits in tissues can lead to organ dysfunction. In the heart, this can cause restrictive cardiomyopathy, while in the nervous system, it can lead to peripheral neuropathy. Histological examination of biopsies from affected organs can provide crucial diagnostic information, confirming the presence of TTR amyloid and guiding treatment decisions.
