What are the Clinical Implications of RNA Complexes?
Understanding RNA complexes has significant clinical implications, particularly in cancer and genetic diseases. Aberrations in RNA processing and regulation can lead to:
Oncogene Activation: Dysregulation of miRNAs can lead to the activation of oncogenes and cancer progression. Genetic Disorders: Mutations affecting RNA-binding proteins or RNA sequences can result in diseases like muscular dystrophy and certain neurodegenerative disorders. Therapeutic Targets: RNA-based therapies, including siRNA and antisense oligonucleotides, are being developed to specifically target disease-related RNA molecules.