Visualization of RNA complexes in tissues is achieved through various histological techniques:
In Situ Hybridization (ISH): This technique uses labeled RNA or DNA probes to detect specific RNA sequences within tissue sections. Immunohistochemistry (IHC): While traditionally used to detect proteins, IHC can also identify RNA-binding proteins, indirectly indicating the presence of RNA complexes. Fluorescence In Situ Hybridization (FISH): A more advanced form of ISH that uses fluorescent probes for higher sensitivity and specificity in detecting RNA molecules.
