What are the Clinical Implications of Nuclear Pleomorphism?
The presence and degree of nuclear pleomorphism have significant clinical implications. High levels of pleomorphism are often associated with more aggressive tumors and poorer patient outcomes. For example, in breast cancer, a high grade of nuclear pleomorphism can indicate a higher likelihood of metastasis and recurrence. Consequently, it plays a vital role in determining the treatment plan, such as the need for more aggressive therapies.