What are the Clinical Implications of MyD88 Dysfunction?
Dysfunction in MyD88 signaling can lead to various clinical conditions. For instance, mutations in the MyD88 gene are associated with increased susceptibility to bacterial infections due to impaired immune responses. Conversely, overactivation of MyD88 signaling has been linked to chronic inflammatory diseases and certain types of cancers. Understanding the role of MyD88 in these conditions can aid in the development of targeted therapies.
