What are the Clinical Implications of Lipase Dysfunction?
Dysfunction in lipase activity can lead to a variety of clinical conditions. Pancreatic insufficiency, where pancreatic lipase production is impaired, results in malabsorption of fats and fat-soluble vitamins. Abnormalities in hepatic lipase function are linked to dyslipidemia and cardiovascular diseases. Defects in hormone-sensitive lipase can lead to issues with fat storage and mobilization, contributing to obesity or metabolic syndrome.
