What are the Clinical Implications of Granular Component Dysfunction?
Dysfunction or structural abnormalities in the granular component can be indicative of certain pathological conditions. For instance, alterations in the GC have been observed in cancer cells, where nucleolar hypertrophy and increased ribosome biogenesis are often seen. Understanding the changes in the GC can provide insights into the molecular mechanisms underlying these diseases and may aid in the development of diagnostic and therapeutic strategies.
