Osteoarthritis: Degradation of chondroitin sulfate in cartilage is a hallmark of osteoarthritis, leading to joint pain and stiffness. Hurler Syndrome: A type of mucopolysaccharidosis caused by a deficiency in alpha-L-iduronidase, leading to the accumulation of dermatan and heparan sulfate. Heparin: A highly sulfated form of heparan sulfate, heparin is widely used as an anticoagulant in medical settings.
