How Do Histological Changes Affect Nerve Conduction?
Histological changes such as demyelination, axonal degeneration, or inflammation can significantly affect nerve conduction. Demyelination, the loss of the myelin sheath, slows down nerve conduction velocities, while axonal degeneration reduces the amplitude of the response. Inflammatory conditions can cause both structural damage and functional impairment, detectable through both histological and NCS evaluations.
