What are the Clinical Implications of Acetylcholinesterase?
AChE inhibitors are commonly used in the treatment of various conditions such as myasthenia gravis and Alzheimer's disease. These inhibitors prolong the action of acetylcholine by preventing its breakdown, thereby enhancing cholinergic transmission. Conversely, exposure to certain toxins like organophosphates can irreversibly inhibit AChE, resulting in toxic accumulation of acetylcholine and severe neuromuscular symptoms.
