What Are the Challenges of Integrating Genome Sequencing with Histology?
Despite its potential, integrating genome sequencing with histology presents several challenges:
Data Complexity: The vast amount of data generated by genome sequencing requires sophisticated computational tools and bioinformatics expertise to analyze and interpret. Tissue Heterogeneity: Tissues are composed of diverse cell types, making it challenging to link specific genetic changes to particular cells or tissue functions. Technical Limitations: Sequencing technologies have limitations in terms of accuracy, read length, and the ability to detect certain types of genetic variations.