What are the Challenges in Visualizing Basement Membranes?
Visualizing basement membranes can be challenging due to their thinness and complex composition. Some common issues include:
Non-specific staining: This can obscure the basement membrane and make interpretation difficult. Tissue artifact: Poor fixation or sectioning can create artifacts that mimic pathological changes. Variability in staining: Different tissues or pathological states may require optimization of staining protocols.
