What are the Challenges in Studying Alpha Synuclein?
Studying alpha synuclein presents several challenges. Its propensity to aggregate complicates the analysis of its native structure and function. Additionally, the protein's dynamic nature and involvement in various cellular processes require sophisticated and sensitive techniques for accurate detection and quantification. The variability in alpha synuclein pathology among different synucleinopathies also adds a layer of complexity to research efforts.