Several techniques have been developed to measure chromatin accessibility. One such method is DNase-seq, which uses DNase I enzyme to cleave accessible DNA regions. Another widely used technique is ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing), which employs a transposase enzyme to insert sequencing adapters into accessible chromatin regions. Both methods generate data that can be analyzed to map accessible regions across the genome.
