whole genome sequencing

What are the Challenges in Integrating WGS with Histology?

1. Data Complexity: The vast amount of data generated by WGS can be overwhelming. Effective data management and analysis require sophisticated [bioinformatics expertise]().
2. Cost: While the cost of sequencing has decreased, it remains relatively high, particularly when combined with traditional histological studies.
3. Interpretation: Linking specific genetic mutations to histological changes can be challenging and requires a multidisciplinary approach involving pathologists, geneticists, and bioinformaticians.

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