What are the Challenges in Histological Diagnosis of Muscular Diseases?
Diagnosing muscular diseases histologically can be challenging due to the heterogeneity of these conditions. Some of the key challenges include:
Sampling Issues: Muscle biopsies may not always capture the affected areas, leading to false negatives. Overlap of Features: Different muscular diseases can exhibit overlapping histological features, complicating the diagnosis. Stage of Disease: The histological appearance of muscle tissue can vary depending on the stage of the disease, requiring correlation with clinical findings.
