What are the Challenges in Discovering New Biomarkers?

Discovering new biomarkers is not without its challenges. Some of the key issues include:

Complexity of Biological Systems: The human body is incredibly complex, and isolating a single biomarker that is both specific and sensitive can be difficult.
Validation: Once a potential biomarker is identified, it must be rigorously validated through clinical trials and other studies to ensure its reliability and utility.
Technological Limitations: Despite advances, there are still limitations in the sensitivity and specificity of current technologies used in biomarker discovery.