1. Diagnosis of Melanoma: The Dopa Reaction helps in identifying melanoma cells, which show increased tyrosinase activity. 2. Research in Melanogenesis: It is used in research to study the process of melanogenesis and the role of various factors in melanin production. 3. Pigmentation Disorders: The reaction aids in diagnosing various pigmentation disorders, such as vitiligo and albinism, by evaluating melanocyte activity.