What is the Histological Structure of Epiphyseal Plates?
The epiphyseal plate is composed of four zones:
1. Resting Zone: This zone contains small, inactive chondrocytes. 2. Proliferative Zone: Here, chondrocytes undergo rapid mitosis, producing new cartilage cells. 3. Hypertrophic Zone: Chondrocytes enlarge and begin to secrete matrix vesicles. 4. Ossification Zone: The cartilage is replaced by bone tissue through the invasion of blood vessels and the formation of osteoblasts.
