In addition to traditional staining, advanced imaging techniques enhance the detection of infectious agents. These include:
Immunohistochemistry (IHC): Utilizes antibodies to detect specific antigens in the tissue, helping to identify particular pathogens. In Situ Hybridization (ISH): Detects specific nucleic acid sequences within the tissue, useful for identifying viral infections. Electron Microscopy: Provides high-resolution images of pathogens at the ultrastructural level, essential for identifying viruses and small bacteria.