In histopathology, differential gene expression is often studied to understand disease mechanisms and identify potential biomarkers. For instance:
Cancer: Tumor cells often exhibit altered gene expression profiles compared to normal cells, which can be used to diagnose and classify cancers or predict treatment responses. Inflammatory diseases: Differential expression of cytokines and other inflammatory mediators can indicate the presence and stage of inflammatory conditions. Neurodegenerative diseases: Changes in the expression of genes involved in neuronal function and survival can provide insights into the progression of diseases like Alzheimer's and Parkinson's.
