What are Some Common Histological Features of Metabolic Disorders?
Different metabolic disorders have distinct histological features. In fatty liver disease, for instance, there is an accumulation of lipid droplets within hepatocytes, which can be visualized using special staining techniques such as Oil Red O. In lysosomal storage diseases, there is an accumulation of undigested substrates within lysosomes, often leading to cell enlargement and organomegaly.