M1 macrophages, also known as classically activated macrophages, are a type of immune cell that plays a pivotal role in the body's immune response. They are a subset of macrophages that are typically activated in response to pathogens and inflammatory stimuli. These cells are characterized by their pro-inflammatory properties and their ability to secrete high levels of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6.
