In histological studies, M1 macrophages can be studied using a combination of techniques including immunohistochemistry (IHC), flow cytometry, and gene expression analysis. IHC allows for the visualization of these cells within tissue sections using antibodies that target specific markers. Flow cytometry can be used to quantify the proportion of M1 macrophages in a cell population. Gene expression analysis helps in understanding the transcriptional profile of these cells and identifying key genes involved in their activation and function.
