What Are Common Problems Encountered with Microtomes?
Some common problems that can arise with microtomes include: - Blade Dullness: This can lead to tearing or compression of the tissue sections. - Misalignment: Incorrect alignment of the blade or specimen holder can cause uneven sections. - Mechanical Failures: Issues such as a malfunctioning specimen holder or a jammed handwheel can interrupt the sectioning process. - Debris Accumulation: Accumulation of paraffin and tissue debris can clog the microtome, affecting its performance.
